This post will guide you through the process of sizing shared memory requirements for database applications running on InterSystems data platforms. It will cover key aspects such as global and routine buffers, gmheap, and locksize, providing you with a comprehensive understanding. Additionally, it will offer performance tips for configuring servers and virtualizing IRIS applications. Please note that when I refer to IRIS, I include all the data platforms (Ensemble, HealthShare, iKnow, Caché, and IRIS).