This post provides guidelines for configuration, system sizing and capacity planning when deploying IRIS and IRIS on a VMware ESXi. This post is based on and replaces the earlier IRIS-era guidance and reflects current VMware and InterSystems recommendations.
Last update Jan 2026. These guidelines are a best effort, remember requirements and capabilities of VMware and IRIS can change.
I jump right in with recommendations assuming you already have an understanding of VMware vSphere virtualization platform.

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