Interoperability on Python (IoP) is a proof-of-concept project designed to showcase the power of the InterSystems IRIS Interoperability Framework when combined with a Python-first approach.IoP leverages Embedded Python (a feature of InterSystems IRIS) to enable developers to write interoperability components in Python, which can seamlessly integrate with the robust IRIS platform. This guide has been crafted for beginners and provides a comprehensive introduction to IoP, its setup, and practical steps to create your first interoperability component. By the end of this article, you will get a clear understanding of how to use IoP to build scalable, Python-based interoperability solutions.

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In the world of APIs, REST is very extended. But what happens when you need more flexibility in your data-fetching strategies? For instance letting the client to choose what fields is going to receive. Enter GraphQL, a query language for your APIs that provides a flexible alternative to REST.

In this post, we will:

  • Compare REST and GraphQL.
  • Dive into the basics of GraphQL: Queries, Mutations, and HTTP.
  • Build a simple GraphQL server implementation using Graphene, SQLAlchemy, and Flask over data in InterSystems IRIS.
  • Explore how to deploy your GraphQL server as a WSGI application in IRIS.
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After so many years of waiting, we finally got an official driver available on Pypi

Additionally, found JDBC driver finally available on Maven already for 3 months, and .Net driver on Nuget more than a month.

As an author of so many implementations of IRIS support for various Python libraries, I wanted to check it. Implementation of DB-API means that it should be replaceable and at least functions defined in the standard. The only difference should be in SQL.

And the beauty of using already existing libraries, that they already implemented other databases by using DB-API standard, and these libraries already expect how driver should work.

I decided to test InterSystems official driver by implementing its support in SQLAlchemy-iris library.

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Learning LLM Magic

The world of Generative AI has been pretty inescapable for a while, commercial models running on paid Cloud instances are everywhere. With your data stored securely on-prem in IRIS, it might seem daunting to start getting the benefit of experimentation with Large Language Models without having to navigate a minefield of Governance and rapidly evolving API documentation. If only there was a way to bring an LLM to IRIS, preferably in a very small code footprint....

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Article
· Apr 15, 2025 6m read
FHIR environment setup guide

I know that people who are completely new to VS Code, Git, Docker, FHIR, and other tools can sometimes struggle with setting up the environment. So I decided to write an article that walks through the entire setup process step by step to make it easier to get started.

I’d really appreciate it if you could leave a comment at the end - let me know if the instructions were clear, if anything was missing, or if there’s anything else you'd find helpful.

The setup includes:

✅ VS Code – Code editor
✅ Git – Version control system
✅ Docker – Runs an instance of IRIS for Health Community
✅ VS Code REST Client Extension – For running FHIR API queries
✅ Python – For writing FHIR-based scripts
✅ Jupyter Notebooks – For AI and FHIR assignments

Before you begin: Ensure you have administrator privileges on your system.

In addition to reading the guide, you can also follow the steps in the videos:

For Windows

https://www.youtube.com/embed/IyvuHbxCwCY
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Article
· Feb 7, 2025 6m read
IRIS %Status and Exceptions Part-2

In this article, exceptions are covered.

Working with Exceptions

Instead of returning a %Status response, you can raise and throw an Exception. You are then responsible for catching the exception and validating it. IRIS provides five main classes to handle exceptions effectively. Additionally, you can create custom exception class definition based on your needs.

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Article
· Mar 17, 2025 2m read
Ollama AI with IRIS

In this article I will be discussing the use of an alternative LLM for generative IA. OpenIA is commonly used, in this article I will show you how to use it and the advantages of using Ollama

In the generative AI usage model that we are used to, we have the following flow:

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Interoperability of systems ensures smooth workflow and management of data in today's connected digital world. InterSystems IRIS extends interoperability a notch higher with its Embedded Python feature, which lets developers seamlessly integrate Python scripts into the IRIS components, like services, operations, and custom functions.

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Article
· Jun 18, 2025 2m read
Options for Python Devs + Poll!

I am writing this post primarily to gather an informal consensus on how developers are using Python in conjunction with IRIS, so please respond to the poll at the end of this article! In the body of the article, I'll give some background on each choice provided, as well as the advantages for each, but feel free to skim over it and just respond to the poll.

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My usecase is sorting and removing duplicates and getting count from a file that has json messages as a individual rows.

I am currently planning to use pandas for this purpose as its really fast. Below are the steps i am following

1) call a python function (called function) from IRIS classmethod(calling function)

2) the call python function will read the json file in a dataframe

3) perform sorting, dup removal, count in the dataframe

4) convert the dataframe into iris stream

5) return back the stream to iris calling function class method

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Hi, Community!

In the previous article, we introduced the Streamlit web framework, a powerful tool that enables data scientists and machine learning engineers to build interactive web applications with minimal effort. First, we explored how to install Streamlit and run a basic Streamlit app. Then, we incorporated some of Streamlit's basic commands, e.g., adding titles, headers, markdown, and displaying such multimedia as images, audio, and videos.

Later, we covered Streamlit widgets, which allow users to interact with the app through buttons, sliders, checkboxes, and more. Additionally, we examined how to display progress bars and status messages and organize the app with sidebars and containers. We also highlighted data visualization, using charts and Matplotlib figures to present data interactively.

In this article, we will cover the following topics:

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Hi Community,

In this article, I will introduce my application iris-AgenticAI .

The rise of agentic AI marks a transformative leap in how artificial intelligence interacts with the world—moving beyond static responses to dynamic, goal-driven problem-solving. Powered by OpenAI’s Agentic SDK , The OpenAI Agents SDK enables you to build agentic AI apps in a lightweight, easy-to-use package with very few abstractions. It's a production-ready upgrade of our previous experimentation for agents, Swarm.
This application showcases the next generation of autonomous AI systems capable of reasoning, collaborating, and executing complex tasks with human-like adaptability.

Application Features

  • Agent Loop 🔄 A built-in loop that autonomously manages tool execution, sends results back to the LLM, and iterates until task completion.
  • Python-First 🐍 Leverage native Python syntax (decorators, generators, etc.) to orchestrate and chain agents without external DSLs.
  • Handoffs 🤝 Seamlessly coordinate multi-agent workflows by delegating tasks between specialized agents.
  • Function Tools ⚒️ Decorate any Python function with @tool to instantly integrate it into the agent’s toolkit.
  • Vector Search (RAG) 🧠 Native integration of vector store (IRIS) for RAG retrieval.
  • Tracing 🔍 Built-in tracing to visualize, debug, and monitor agent workflows in real time (think LangSmith alternatives).
  • MCP Servers 🌐 Support for Model Context Protocol (MCP) via stdio and HTTP, enabling cross-process agent communication.
  • Chainlit UI 🖥️ Integrated Chainlit framework for building interactive chat interfaces with minimal code.
  • Stateful Memory 🧠 Preserve chat history, context, and agent state across sessions for continuity and long-running tasks.

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InterSystems Official
· Nov 19, 2025
Client SDKs available on external repositories

Hi community!

I am excited to say that since the beginning of this year we have published many of the client SDKs for InterSystems IRIS, InterSystems IRIS for Health and Health Connect to the corresponding external repositories (Maven, NuGet, npm and PyPI). This provides many benefits to you such as:

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Introduction

In InterSystems IRIS 2024.3 and subsequent IRIS versions, the AutoML component is now delivered as a separate Python package that is installed after installation. Unfortunately, some recent versions of Python packages that AutoML relies on have introduced incompatibilities, and can cause failures when training models (TRAIN MODEL statement). If you see an error mentioning "TypeError" and the keyword argument "fit_params" or "sklearn_tags", read on for a quick fix.

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Apache Airflow is the leading open-source platform to programmatically author, schedule, and monitor data pipelines and workflows using Python. Workflows are defined as code (DAGs), making them version-controlled, testable, and reusable. With a rich UI, 100+ built-in operators, dynamic task generation, and native support for cloud providers, Airflow powers ETL/ELT, ML pipelines, and batch jobs at companies like Airbnb, Netflix, and Spotify.

Airflow Application Layout

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Hi all,

Let's do some more work about the testing data generation and export the result by REST API.😁

Here, I would like to reuse the datagen.restservice class which built in the pervious article Writing a REST api service for exporting the generated patient data in .csv

This time, we are planning to generate a FHIR bundle include multiple resources for testing the FHIR repository.

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Hi Community,

In the first part of this series, we examined the fundamentals of Interoperability on Python (IoP), specifically how it enables us to construct such interoperability elements as business services, processes, and operations using pure Python.

Now, we are ready to take things a step further. Real-world integration scenarios extend beyond simple message handoffs.They involve scheduled polling, custom message structures, decision logic, filtering, and configuration handling.In this article, we will delve into these more advanced IoP capabilities and demonstrate how to create and run a more complex interoperability flow using only Python.

To make it practical, we will build a comprehensive example: The Reddit Post Analyzer Production. The concept is straightforward: continuously retrieving the latest submissions from a chosen subreddit, filtering them based on popularity, adding extra tags to them, and sending them off for storage or further analysis.

The ultimate goal here is a reliable, self-running data ingestion pipeline. All major parts (the Business Service, Business Process, and Business Operation) are implemented in Python, showcasing how to use IoP as a Python-first integration methodology.

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Are you curious about how to run Python scripts directly in your InterSystems IRIS or Caché terminal? 🤔 Good news it's easy! 😆 IRIS supports Embedded Python, allowing you to use Python interactively within its terminal environment.

How to access the Python Shell?

To launch the Python shell from the IRIS terminal, simply run the following command:

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Introduction

To achieve optimized AI performance, robust explainability, adaptability, and efficiency in healthcare solutions, InterSystems IRIS serves as the core foundation for a project within the x-rAI multi-agentic framework. This article provides an in-depth look at how InterSystems IRIS empowers the development of a real-time health data analytics platform, enabling advanced analytics and actionable insights. The solution leverages the strengths of InterSystems IRIS, including dynamic SQL, native vector search capabilities, distributed caching (ECP), and FHIR interoperability. This innovative approach directly aligns with the contest themes of "Using Dynamic SQL & Embedded SQL," "GenAI, Vector Search," and "FHIR, EHR," showcasing a practical application of InterSystems IRIS in a critical healthcare context.

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