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10:47 AM — Jose Garcia's creatinine test results arrive at the hospital FHIR server.
2.1 mg/dL — a 35% increase from last month.

What happens next?

  • Most systems: ❌ The result sits in a queue until a clinician reviews it manually — hours or days later.
  • This system: 👍 An AI agent evaluates the trend, consults clinical guidelines, and generates evidence-based recommendations — in seconds, automatically.

No chatbot. No manual prompts. No black-box reasoning.

This is event-driven clinical decision support with full explainability:

image

Triggered automatically by FHIR events
Multi-agent reasoning (context, guidelines, recommendations)
Complete audit trail in SQL (every decision, every evidence source)
FHIR-native outputs (DiagnosticReport published to server)

Built with:
- InterSystems IRIS for Health — Orchestration, FHIR, persistence, vector search
- CrewAI — Multi-agent framework for structured reasoning

You'll learn: 🖋️ How to orchestrate agentic AI workflows within production-grade interoperability systems — and why explainability matters more than accuracy alone.

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How I Vibecoded a Backend (and Frontend) on InterSystems IRIS

I wanted to try vibecoding a real backend + frontend setup on InterSystems IRIS, ideally using something realistic rather than a toy example. The goal was simple: take an existing, well-known persistent package in IRIS and quickly build a usable UI and API around it — letting AI handle as much of the boilerplate as possible. Here is the result of the experiments.

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Intersystems IRIS Productions provide a powerful framework for connecting disparate systems across various protocols and message formats in a reliable, observable, and scalable manner. intersystems_pyprod, short for InterSystems Python Productions, is a Python library that enables developers to build these interoperability components entirely in Python.

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We are attempting to "Repoint" old class data to new class data to save disk space and data redundancy across multiple tables. This works to a point. In essence the two classes are sharing the same data / Index / stream globals. But if an ID in the Old_Class is opened, a property is modified, and saved the property that is in the New_Class (but not in the Old_Class) is NULLed / blanked.

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Hi Community,

We're happy to announce that registration for the event of the year — InterSystems Ready 2026 — is now open. This is the premier global summit for the InterSystems technology community – a gathering of industry leaders and developers at the forefront of their respective industries. This event attracts a wide range of attendees, from C-level executives, top subject matter experts and visionary leaders, managers, directors and developers. Attendees gather to network with peers, connect with InterSystems partners, learn best practices and get a firsthand look at upcoming features and future innovations from InterSystems.

➡️ InterSystems Ready 2026

🗓 Dates: April 27 - 30, 2026

📍 Location: Gaylord National Resort & Convention Center, National Harbor, Maryland, USA

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Hi Community!

We’re excited to announce the launch of a new, hands-on training program:

🧑‍💻 Developing FHIR Applications Using Python 🧑‍💻

This cohort-based course takes developers from FHIR fundamentals to advanced, real-world healthcare interoperability solutions, with deeper, more practical coverage than typical industry offerings and a strong focus on production-ready skills using InterSystems technology.

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Hello DC community,

InterSystems Certification is currently developing a certification exam for ObjectScript developers, and if you match the exam candidate description below, we would like you to beta test the exam! The exam will be available for beta testing starting February 18th, 2026.

Beta testing will be completed May 4, 2026.

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Hi,

I'm having a problem with %JSON.Adaptor and "list of" binding.

For exemple, this class with a property "oazisCode As list of %String".

Class User.ADGroup Extends (%Persistent, %JSON.Adaptor)

{
/// Code interne
Property code As %String;

/// Libellé
Property text As %String(MAXLEN = "");

Property oazisCode As list Of %String;

}

The first time call to %JSONImport works properly

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In this article, I aim to demonstrate a couple of methods for easily adding validation to REST APIs on InterSystems IRIS Data Platform. I believe a specification-first approach is an excellent idea for API development. IRIS already has features for generating an implementation stub from a specification and publishing that specification for external developers (use it with iris-web-swagger-ui for the best results). The remaining important thing not yet implemented in the platform is the request validator. Let's fix it!

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Hey Community!

We're happy to share a new video from our InterSystems Developers YouTube:

Optimizing Query Performance in Health Insight @ Ready 2025

https://www.youtube.com/embed/s9CIi1HQ_iQ
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I need to reproduce a table (in fact a view, but let's start with a simple table 😊) in IRIS as the currently used in Oracle.

I need to expose/project one column to JDBC as CLOB, in my class I have the corresponding property defined as:

Property GlobStream As %Stream.GlobalCharacter;

In JDBC this column is projected as LONGVARCHAR, this is compliant with the documentation but I need to project it as CLOB.

In addition, I'm no expert in JDBC but wit seems that LONGVARCHAR has a Maximum Length 32,700 characters in JDBC, not quite enough for an arbitrary stream.

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Hey Developers,

Watch this video to learn about automating the provisioning and management of FHIR services:

Automating Provisioning and Management of FHIR Services @ Ready 2025

https://www.youtube.com/embed/QqA92pDISI4
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Hi, Community!

👩‍⚕️If you need to access clinical data at scale, the InterSystems Bulk FHIR Coordinator can help!

Using the InterSystems Bulk FHIR Coordinator to Extract Clinical Data

https://www.youtube.com/embed/DFiHQYhDGMo?utm_source=youtube&utm_medium=social&utm_campaign=DFiHQYhDGMo
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