After we rolled out a new cointainer based on containers.intersystems.com/intersystems/irishealth:2023.1 this week, we suddenly noticed that our FHIR Repository started responding with an Error 500. This turns out to be caused by PROTECT violations on the new HSSYSLOCALTEMP namespace and database used by this version of the IRIS for Health FHIR components.
The trick to solve that is to add the "%DB_HSSYSLOCALTEMP" to the Web Application(s) that handle FHIR Requests. You can script that by running the following Class method in the namespace(s) that define these Web Applications:
do ##class(HS.H.png)

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If you are new to InterSystems Certification, please review our 
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