#InterSystems IRIS for Health

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InterSystems IRIS for Health™ is the world’s first and only data platform engineered specifically for the rapid development of healthcare applications to manage the world’s most critical data. It includes powerful out-of-the-box features: transaction processing and analytics, an extensible healthcare data model, FHIR-based solution development, support for healthcare interoperability standards, and more. All enabling developers to realize value and build breakthrough applications, fast. Learn more.

Question Robert Hildebrand · Feb 5

Hi,

I want to consume an API that provides HL7 messages. To achieve this, I have thought of the following workflow:

I have created a business service that periodically triggers a business process. The trigger request is forwarded to a business operation. There, a %Net.HttpRequest is assembled from scratch and then sent to the API endpoint. The corresponding HttpResponse then contains several HL7 messages encoded in UTF-8 in the message body. To further process the HL7 messages, the operation sends the HttpResponse back to the business process as EnsLib.HTTP.GenericMessage.

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Question Scott Roth · Feb 5

I have always struggled with Iterating through a JSON response to pull out certain fields into a Data Class Structure to use to populate fields in a DTL. So I defined the whole structure for the following JSON, with the base structure extending Ens.Response, %XML.Adaptor, and %JSON.Adaptor.

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InterSystems Official Daniel Palevski · Feb 3

The third developer previews of InterSystems IRIS® data platform, InterSystems IRIS® for Health, and HealthShare® Health Connect 2026.1 have been posted to the WRC developer preview site.  Containers can be found on our container registry and are tagged latest-preview.

These developer previews includes the dropping of Mac Intel support starting from 2026.1.0, and the adding back of Windows Server 2019 support to 2026.1.0.

Initial documentation can be found at these links below:

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Article Gabriel Ing · Feb 6 8m read

TL;DR This article explains how to deploy InterSystems IRIS Community Edition on Azure using the Azure Marketplace and a Virtual Machine. It covers prerequisites, instance selection, authentication, SSH access, first verification steps, and how to delete resources to avoid charges. The deployment can typically be done using Azure free credits and is suitable for developers who want to quickly start working with IRIS in the cloud.

Who this guide is for. This guide is intended for developers, solution architects, and DevOps engineers who want to deploy InterSystems IRIS Community Edition on Microsoft Azure. No prior Azure automation experience is required, but basic familiarity with the Azure Portal and SSH is helpful.

After following this guide, you will be able to:

  • Launch InterSystems IRIS Community Edition from the Azure Marketplace
  • Configure a small, secure Azure VM
  • Connect to IRIS using SSH and the Management Portal
  • Reset the default IRIS password and verify that IRIS is running

Prerequisites

  • An active Azure subscription (new accounts may have free credits)
  • Permissions to create resource groups, VMs, and networking resources
  • An SSH client and a private key (.pem) you can store securely
  • Basic knowledge of Linux command line

Deployment overview

  • Open the IRIS Community Edition listing in Azure Marketplace and click Get it now
  • In Azure Portal, choose Start with a pre-set configuration (or Create)
  • Configure Basics: subscription, resource group, VM name, region, image, and size (a small VM is usually sufficient)
  • Choose SSH key authentication and generate/download the key if needed
  • Review + Create, accept terms, and deploy; then Go to resource → Connect → SSH
  • First SSH login: run iris password to change _SYSTEM/SYS; start a session with iris session iris
  • Management Portal: http://YOUR_VM_IP:52773/csp/sys/UtilHome.csp
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Article Alberto Fuentes · Feb 13 10m read

10:47 AM — Jose Garcia's creatinine test results arrive at the hospital FHIR server. 2.1 mg/dL — a 35% increase from last month.

What happens next?

  • Most systems: ❌ The result sits in a queue until a clinician reviews it manually — hours or days later.
  • This system: 👍 An AI agent evaluates the trend, consults clinical guidelines, and generates evidence-based recommendations — in seconds, automatically.

No chatbot. No manual prompts. No black-box reasoning.

This is event-driven clinical decision support with full explainability:

image

Triggered automatically by FHIR events ✅ Multi-agent reasoning (context, guidelines, recommendations) ✅ Complete audit trail in SQL (every decision, every evidence source) ✅ FHIR-native outputs (DiagnosticReport published to server)

Built with:

  • InterSystems IRIS for Health — Orchestration, FHIR, persistence, vector search
  • CrewAI — Multi-agent framework for structured reasoning

You'll learn: 🖋️ How to orchestrate agentic AI workflows within production-grade interoperability systems — and why explainability matters more than accuracy alone.

<iframe width="560" height="315" src="https://www.youtube.com/embed/43Vl7cU_uNY?si=o3NZ3AqPOdFkCn9w" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe>
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Article Luis Angel Pérez Ramos · Apr 18, 2025 3m read

Who hasn't been developing a beautiful example using a Docker IRIS image and had the image generation process fail in the Dockerfile because the license under which the image was created doesn't contain certain privileges?

In my case, what I was deploying in Docker is a small application that uses the Vector data type. With the Community version, this isn't a problem because it already includes Vector Search and vector storage. However, when I changed the IRIS image to a conventional IRIS (the latest-cd), I found that when I built the image, including the classes it had generated, it returned this error:

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Article Ben Schlanger · Mar 15, 2024 4m read

When using InterSystems IRIS as an interoperability engine, we all know and love how easy it is to use the Message Viewer to review message traces and see exactly what's going on in your production. When a system is handling millions of messages per day, you may not know exactly where to begin your investigation though.

Over my years supporting IRIS productions, I often find myself investigating things like...

  • What sort of throughput does this workflow have?
  • Where is the bottleneck?
  • What are my most common
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Article Luis Angel Pérez Ramos · Jan 28 5m read

How many times have you had to receive or generate a JSON and wished you could work on it using DTLs without having to deal with DynamicObjects trying to remember the name of each field? Do you want to break down and make your giant JSON file more digestible?

In my case, never, but I thought that someone might find it useful to have a feature that captures your JSON and breaks it down into a series of ObjectScript classes that you can work with more easily and conveniently.

Well then...behold JSON2Class in all its glory!

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Job Ratnesh Shrivastava · Jan 27

Job Title: InterSystems Developer / Specialist (IRIS / HealthShare)
Location: New York City, NY (Hybrid / Remote)
Duration: Contract (2+ years)
Experience: Min. 8 Years 


Job Summary

We are looking for an experienced InterSystems Developer / Specialist with expertise in InterSystems IRIS / HealthShare to support healthcare integration and interoperability initiatives. The ideal candidate should have hands-on experience in ObjectScript development, healthcare data standards, and integration protocols supporting EHR/HIE environments.


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Article Ashok Kumar T · Jan 14 14m read

What is a FHIR Profile?

A FHIR profile is a collection of rules and constraints used to customize and refine a base Fast Healthcare Interoperability Resources (FHIR) resource. Profiling is a vital process that adapts the base FHIR resource standard to satisfy the unique requirements of a specific use case, geographic region, medical institution, or clinical workflow.

While the base FHIR specification provides generic, flexible definitions for resources (such as Patient, Observation, or Medication), profiles transform these generic resources into more precise ones. This ensures consistent and interoperable data exchange tailored for a particular community or implementation.

FHIR is designed to cover various healthcare scenarios globally. Profiles allow implementers to adapt this general platform without losing the benefits of standardization.

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Article Sylvain Guilbaud · Jan 23 5m read

 

A question that quickly arises when configuring IAM (aka Kong Gateway) is how many routes should be created to reach all the business objects in an IRIS API.

A common mistake is to create one route per business object, unnecessarily multiplying the number of routes.

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Article Yuri Marx · May 5, 2025 10m read

RabbitMQ is a message broker that allows producers (those who send a data message) and consumers (those who receive a data message) to establish asynchronous, real-time, and high-performance massive data flows. RabbitMQ supports AMQP (Advanced Message Queuing Protocol), an open standard application layer protocol. 
The main reasons to employ RabbitMQ include the following:

  • You can improve the performance of the applications using an asynchronous approach.
  • It lets you decouple and reduce dependencies between services, microservices, and applications with the help of a data message mediator, meaning that there is no need for producers and consumers of exchanged data to know each other.
  • It allows the long-running processing of sent data (with the results) to be delivered after utilizing a response queue.
  • It helps you migrate from monolithic to microservices, where microservices exchange data via Rabbit in a decoupled and asynchronous way.
  • It offers reliability and resilience by making it possible for messages to be stored and forwarded. A message can be delivered multiple times until it is processed.
  • Message queueing is the key to scaling your application. As the workload increases, you will only have to add more workers to handle the queues faster.
  • It works well with data streaming applications.
  • It is beneficial for IoT applications.
  • It is a must for Bots’ communication.
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Job Tricia Scanlon · Jan 19

We are hiring!  100% Remote W2 Contract | 3-6+ Months (numerous extensions likely)

Two Roles:
🔹InterSystems Engineer
🔹Epic Bridges Certified/InterSystems Engineer  

Having solid experience with the below: 

  • Interface Development: Building and configuring message routes, business processes, and transformations using components like IRIS, Ensemble, or HealthShare.
  • Interoperability Standards: Implementing and supporting workflows for healthcare standards including HL7 (v2/v3), FHIR, etc.
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Article Kate Lau · Jan 5 3m read

Hi, now I would like to continuous on the topic that we talk about previously

Using Postman for testing the OAuth2.0 of the InterSystems FHIR repository - Part1

 


Question 1: Where is my client_id and client_secret come form?

Short answer: Authentication Server.

 

If you don't have an Authentication Server, you may set up one as following

 

Provide the hostname (the host must support Https), at least 1 grand type (we choose client credential here), and SSL/TSL configuration

 

Input the scopes (here we input user/*.read and user/*.

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Article Ashok Kumar T · Feb 17, 2025 6m read

What is JWT?

JWT (JSON Web Token) is an open standard (RFC 7519) that offers a lightweight, compact, and self-contained method for securely transmitting information between two parties. It is commonly used in web applications for authentication, authorization, and information exchange.

A JWT is typically composed of three parts:

1. JOSE (JSON Object Signing and Encryption) Header
2. Payload
3. Signature

These parts are encoded in Base64Url format and concatenated with dots (.) separating them.

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Question Dmitrii Baranov · Jan 14

I have a Postgres table which should be migrated to IRIS. The table has a computed column, like:

CREATE TABLE example_table (
    id VARCHAR(10) PRIMARY KEY,
    normalized_id VARCHAR(10) GENERATED ALWAYS AS (LPAD(id, 10, '0')) STORED
);

IRIS also has the LPAD function but I can't figure out how to achieve the same result using pure SQL DDL.

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Question Michael Derr · Dec 4, 2025

We are a group of interface analysts in a healthcare setting, running IRIS for Health 2024, having upgraded over time from an old ENSEMBLE environment.  We have been working on a wish list of development goals, but are having trouble finding the correct, best practice method/path for getting to what we envision.

Current state:  We run IRIS for Health on a Redhat 8 virtual machine.  We run Interoperability productions (IE.cls) out of 6 namespaces.  We have a dev/test box and a production box.

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Article Vachan C Rannore · Dec 28, 2025 1m read

SET assigns value to the variable at RUNTIME.

#DIM declare the variable and it's Data Type at COMPILE TIME.







SET #DIM
Makes the variables Dynamic. Improves Readability.
No Data Type Declaration. Enables IDE auto-completion.
Runtime Useful for Object references.

#DIM name As %String
Set name = "Micheal Scott"
#DIM age As %Numeric
Set age = 36
#DIM employer As App.Employer               ; compile time
Set employer = ##class(App.Employer).%New() ; runtime 

 

SET or #DIM? Your design, your rules.

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Announcement Larry Finlayson · Jan 13

Managing InterSystems Servers – Virtual  February 2-6, 2026

  • Configure, manage, plan, and monitor system operations of InterSystems Data Platform technology
  • This 5-day course teaches system and database administrators how to manage InterSystems® Data Platform technology which powers all of our products.
  • Learn to install, configure and secure the data platform, configure for high availability and disaster recovery, and monitor the system.
  • Students also learn troubleshooting techniques.

SELF REGISTER HERE

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Question Preedhi Garg · Jan 12

I’m working on XML Digital Signature in InterSystems IRIS using %XML.Security.Signature

I start with an XML document that is created by parsing an input XML string, and I want to digitally sign this document using an X509 certificate.

Set x509 = ##class(%SYS.X509Credentials).GetByAlias(credAlias)
Set signature = ##class(%XML.Security.Signature).CreateX509(x509,$$$SOAPWSIncludeNone ,$$$KeyInfoX509Certificate)

Set signature.Id = "SIG1"
DO signature.SetSignatureMethod($$$SOAPWSrsasha1)
DO signature.SetDigestMethod($$$SOAPWSsha1)
Set signature.SignedInfo.CanonicalizationMethod.
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