I think I already know the answer to this but I thought I'd ask anyway. So the Node.js adapter allows you to perform operations directly on Globals. Does the InterSystems.Data.CacheClient.dll or InterSystems.CacheExtreme.dll provide a mechanism to access Gobals directly or are you accessing globals via Caché ObjectScript classes?
Beginner tag unites articles and questions for those who are getting started with InterSystems Data Platform

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