I'm not so experienced in administering IRIS but as far as I understand IRIS for Health community comes with a web server out-of-the-box while licensed editions require Web Gateway to be deployed.
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InterSystems IRIS for Health™ is the world’s first and only data platform engineered specifically for the rapid development of healthcare applications to manage the world’s most critical data. It includes powerful out-of-the-box features: transaction processing and analytics, an extensible healthcare data model, FHIR-based solution development, support for healthcare interoperability standards, and more. All enabling developers to realize value and build breakthrough applications, fast. Learn more.