Web Gateway/Apache configuration to make SOAP Client Requests?

I am having issues trying to send SOAP requests to a Cloud Based AWS Application that lives outside of our network. 

It is using a Basic Authentication, Key, Certificate Authority and Whitelist for Security. 

If I attempt the connection using wget from the command line I am able to connect,

:>wget --bind-address=10.95.129.245 --server-response https://xxxxxxxxxx/xxxxxxx/services/Mirth
--2025-06-06 15:54:51--  https://xxxxxxx/xxxxxxxx/services/Mirth
wget: /ensemble/.netrc:16: unknown token xxxxxxx
wget: /ensemble/.netrc:16: unknown token xxxxxxxx
Resolving xxxxxxx.com (xxxxxxx)... 34.233.89.102, 54.165.234.62
Connecting to hcis-staging.cbord.com (xxxxxxxx)|xxxxxxx|:443... connected.
HTTP request sent, awaiting response...
  HTTP/1.1 200 OK
  Cache-control: no-cache="set-cookie"
  Content-Type: text/html; charset=utf-8
  Date: Fri, 06 Jun 2025 19:54:51 GMT
  Server: nginx
  Set-Cookie: AWSELB=D507B3110AAE4C39FED576EDFCA8C486670B04F18A5E3BBF0AE38321B36B528F14A78096B862E1C523ADEB028C4EB54BB3C1A6750FC29A6832764251160DDA704F73127995;PATH=/
  Set-Cookie: AWSELBCORS=D507B3110AAE4C39FED576EDFCA8C486670B04F18A5E3BBF0AE38321B36B528F14A78096B862E1C523ADEB028C4EB54BB3C1A6750FC29A6832764251160DDA704F73127995;PATH=/;SECURE;SAMESITE=None
  Content-Length: 754
  Connection: keep-alive
Length: 754 [text/html]
Saving to: 'Mirth'
 

however when I attempt from a Business Operation I am getting....

06/06/2025 15:51:49.8039637 *********************
Output from Web client with SOAP action = http://xxxxxxxx/msg/SendMessage
<?xml version="1.0" encoding="UTF-8" ?>
<SOAP-ENV:Envelope xmlns:SOAP-ENV='http://schemas.xmlsoap.org/soap/envelope/' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xmlns:s='http://www.w3.org/2001/XMLSchema'>
  <SOAP-ENV:Body><SendMessage xmlns="http://xxxxxxxxx/msg/"><key xsi:type="s:string">xxxxxxxxxxxxxxx</key><encodedMessage xsi:type="s:string">xxxx@EnsLib.HL7.Message</encodedMessage></SendMessage></SOAP-ENV:Body>
</SOAP-ENV:Envelope>

06/06/2025 15:51:54.8081368 *********************
Input to Web client with SOAP action = http://xxxxxxx/msg/SendMessage

ERROR #6059: Unable to open TCP/IP socket to server xxxxxxx:443
string**** SOAP client return error. method=SendMessage, action=http://xxxxxxxx/msg/SendMessage
     ERROR #6059: Unable to open TCP/IP socket to server xxxxxxxxxx:443

Within the Business Operation class, I was able to define the Local Interface it should use.

Class osuwmc.Nutrition.OSU.CBORD.Operation.CBORDHL7Port Extends Ens.BusinessOperation [ ProcedureBlock ]
{

Parameter ADAPTER = "EnsLib.SOAP.OutboundAdapter";

Property LocalInterface As %String(MAXLEN = 255);

Parameter SETTINGS = "LocalInterface:Connection:selector?context={Ens.ContextSearch/TCPLocalInterfaces}";

Method OnInit() As %Status
{
 IF '$IsObject(..Adapter.%Client.HttpRequest) {
	set ..Adapter.%Client.HttpRequest = ##class(%Net.HttpRequest).%New()
 }
 set ..Adapter.%Client.HttpRequest.LocalInterface = $ZStrip($P(..LocalInterface,"("),"*W")

	quit $$$OK
}

Method SendMessage(pRequest As osuwmc.Nutrition.OSU.CBORD.Request.SendMessageRequest, Output pResponse As osuwmc.Nutrition.OSU.CBORD.Response.SendMessageResponse) As %Library.Status
{
 Set ..Adapter.WebServiceClientClass = "CBORDHL7WSService.CBORDHL7Por.....

Do I have to do something special with the Web Gateway and Apache Web Service to allow the connection out?