This is very easy to setup a FHIR server in InterSystems IRIS for Health.
It could be even one IPM command with this package:
USER>zpm "install fhir-server"
But which FHIR portal could you recommend to use?
I used to work with this one, which is very easy to install too:
USER>zpm "install fhir-portal"
but it doesn't work at the moment and I'm not sure if its main contributors @José Roberto Pereira and @Henrique Dias plan to support it.
What do you use? What do you recommend? Ideally installable with IPM package manager. Thanks!