Architectural Question about receiving HL7 via HTTPS

For those that use IRIS for Health, HealthShare, and or Health Connect...

As Health Applications are moving to the Cloud, how have you handled communication from the Application to your instances via HTTPS?

Trying to figure out the best path on designing the proper workflow to allow these messages to be allowed to be eventually sent to our EMR to post to the patient chart.

We are very wary of opening a connection from the internet to our instance of Health Connect.

Thanks