Hey Community,

Enjoy the new video on InterSystems Developers YouTube:

Advancing Healthcare Interoperability - Strategy and Vision @ Ready 2025

https://www.youtube.com/embed/_1mBIv-lGco
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Contestant

10:47 AM — Jose Garcia's creatinine test results arrive at the hospital FHIR server.
2.1 mg/dL — a 35% increase from last month.

What happens next?

  • Most systems: ❌ The result sits in a queue until a clinician reviews it manually — hours or days later.
  • This system: 👍 An AI agent evaluates the trend, consults clinical guidelines, and generates evidence-based recommendations — in seconds, automatically.

No chatbot. No manual prompts. No black-box reasoning.

This is event-driven clinical decision support with full explainability:

image

Triggered automatically by FHIR events
Multi-agent reasoning (context, guidelines, recommendations)
Complete audit trail in SQL (every decision, every evidence source)
FHIR-native outputs (DiagnosticReport published to server)

Built with:
- InterSystems IRIS for Health — Orchestration, FHIR, persistence, vector search
- CrewAI — Multi-agent framework for structured reasoning

You'll learn: 🖋️ How to orchestrate agentic AI workflows within production-grade interoperability systems — and why explainability matters more than accuracy alone.

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Sometimes it is more convenient, more efficient, and more secure, to limit FHIR Searches per pre-defined "Lists" of Resources.

Since v2025.1 we support several List-related features in our FHIR Server.

I will highlight these here, and provide some samples.

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Hey Community,

Enjoy the new video on InterSystems Developers YouTube:

Developing on FHIR in 2025 @ Ready 2025

https://www.youtube.com/embed/rmLd7NH6AbY
[This is an embedded link, but you cannot view embedded content directly on the site because you have declined the cookies necessary to access it. To view embedded content, you would need to accept all cookies in your Cookies Settings]

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Question
· Dec 30, 2025
HealthShare - FHIR gateway

I'm new to HealthShare. I've installed a demo using the HS.Util.Installer helper, now I'm playing with its FHIR Gateway (which is the HSFHIR namespace). When I try to create a new resource of type Patient using HTTP POST, HealthShare responses with

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Hi,
Our production FHIR server is populated by several processes from several sources,
some of those sources send test data or wrong data (by mistake or as part of an integration test),
the data is consumed by our BI every 15 minutes.
when I mark a resource as test (using meta security) BI knows to update it on their system.
everything is fine up to here (except that there is test data in Prod)
my problem is that if someone send the same patient again it will recreate the patient without the security tag.
any thoughts?

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InterSystems API Manager (IAM) is a core component of the InterSystems IRIS Data Platform, offering centralized API management with a strong emphasis on security. IAM simplifies the entire API lifecycle, from creation to retirement, and provides a developer portal for easy API discovery and integration. Access control features allow administrators to define precise permissions, and IAM seamlessly integrates with the IRIS Data Platform, enhancing data management and integration capabilities.

Features of IAM include:

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Article
· Dec 24, 2025 2m read
"The Hidden HTTP Errors" (Behind IIS)

You send an HTTP request and get back an HTTP error but with an HTML error page which you didn't expect... what's happening?... 🤔

Specifically for example, perhaps you tried to READ a FHIR Resource (e.g. /Patient/123) and you get back a 404 error page, even though with other Patient IDs, you get back the Resource payload, so "the page" definitely does exist... why should you be getting a 404 error page? 🙄

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