It was solved by WRC (InterSystems Support).
Anyway, the code above should work fine as tested by WRC. You can use HttpRequest.Post(tURL, 1, 1) to just display the request on the current device and compare it with the request sent by Postman, if there are any differences.
If you are a supported customer (with the license under support - SUTA), please contact WRC. More details you can find at https://www.intersystems.com/support/
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What is the setting of the OSUWMC?Nutrition.OSU.CBORD.Operation.CBORDHL7Port operation in your production? Could you please provide the Basic and Connection Settings?
Have you set the SSL Configuration there?
My suspicion is that you either sent an HTTP request instead of an HTTPS request to the 443 (SSL) port or that the SSL Configuration is not set.