An integrity check also treats it as if it was a single file. This is only going to be more of an issue as the max size increses.

There is no other option for integrity check because in multi volume database a global can span across multiple volumes/files and a global structure must be fully scanned to check integrity.

If this is a concern, maybe splitting a global across multiple "small" (the concept of small may vary! 😁) database using subscript mapping can be an option.
Integrity check is performed at database/global level, not namespace/global level.

You may have the option of using Extended Global References and in particular Bracket Syntax with References to Databases.

In your code you need to change all your global references from:
^SYS("CommonConfig")
to
^[%dbConfig]SYS("CommonConfig")

Then, for normal situation where you want the %ALL mapping to apply, just use:
set %dbConfig=""
When you need to explicitly map it to a BARCONFIG database, then:
set %dbConfig="^^:ds:BARCONFIG"

This way you can switch from default %ALL mapping to "explicit reference" within your code.
In the example I used a % local variable (%dbConfig) to hold the "database name reference" because it has a global scope, you may use a different approach like a property in some of your classes, a macro with some reference (in a global?) or...whatever is appropriate for your environment.

irislib database is mounted as readonly database, so journal is disabled.

irislocaldata database contains items used internally by IRIS and journal is disabled by design.

This is standard/normal in any IRIS installation.

I doubt your issue is caused by these journal being disabled and I would not tamper default/standard journal configuration for system databases.

The first parameter (Lookup Table Name) of Exists function must be quoted: Exists("HologicProcedureFilter",.....)

If you want, you can switch to the old zen based rule editor, in the upper right of the page click on the user icon and select Open in Zen rule editor:

Note that it will open the rule in new tab, leaving the old tab open, make sure you use only one tab to edit the rule!