These types of questions are probably best answered by sending an e-mail to email@example.com and the WRC could walk through this with you.
If I had to take a guess, I would say that you should look at the Business Process HS.Gateway.ECR.Process and look at the setting for "ECRTarget" and "GatewayOperations" to make sure they have values. It looks like it could be blank and causing a <SUBSCRIPT> error when trying to send a message to a missing target.
I would check to see if the user that is logged in has a role that has the resource (%HSAdmin_HubManagment) with "USE" access defined. Are you using a custom HOME UI class? If so, check the restrictions added to the custom class.
If this doesn't solve your problem, please enter an issue in the WRC and they will help you with your issue.
In Ensemble 2016.1 (and HealthShare builds based on 2016.1) there is a new feature that monitors activity volume, check out:
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