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I mostly use Embedded Python but without the language tag : [ language = python ] in objectscript classes, in my opinion it doesn't make senses to mix two languages in one file.
Why Embedded Python mostly because it's faster and it's in the DNA of intersystems compute close to the data.
Now, time to time, i also use DB-API with sqlalchmy, to manipulate SQL data, thanks to the community edition of DB-API for IRIS, i can chose if i want to use it remotly or with Embedded Python.
At the end of the day, it should not have any difference between embedded python or "native API".
I'm doing the same with the triple-slash, it's working fine on iris 2024.3 and 2025.1 with firefox.
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Official, IRIS support only one version of python and one set of library (default in <installdir/mgr/python).
But you can find here a PoC of venv support in our interoperabilty framework https://grongierisc.github.io/interoperability-embedded-python/venv/.
The good new is that each componement of the interoperabilty has it's own process, it means it can run different version of python.
Remember it's a PoC and it's community based.
Give it a try, and let me know what you think of it.