Hello @Ward De Backer, 

Have you tested this with IRIS?

I am trying to run it using your guide and the documentation (https://docs.intersystems.com/irislatest/csp/docbook/DocBook.UI.Page.cls?KEY=BXJS_connect), and I have this error:

var db = new irisobj.Iris();

TypeError: irisobj.Iris is not a constructor

I am using node v8.6.0 and iris.800.node.

My code is almost the same as yours:

let irisobj = require('iris');
var db = new irisobj.Iris();
console.log('Intersystems IRIS instance: ', db);