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· 10 hr ago 14m read
Implementing FHIR Profiles on IRIS

What is a FHIR Profile?

A FHIR profile is a collection of rules and constraints used to customize and refine a base Fast Healthcare Interoperability Resources (FHIR) resource. Profiling is a vital process that adapts the base FHIR resource standard to satisfy the unique requirements of a specific use case, geographic region, medical institution, or clinical workflow.

While the base FHIR specification provides generic, flexible definitions for resources (such as Patient, Observation, or Medication), profiles transform these generic resources into more precise ones. This ensures consistent and interoperable data exchange tailored for a particular community or implementation.

FHIR is designed to cover various healthcare scenarios globally. Profiles allow implementers to adapt this general platform without losing the benefits of standardization.

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Contestant

10:47 AM — Jose Garcia's creatinine test results arrive at the hospital FHIR server.
2.1 mg/dL — a 35% increase from last month.

What happens next?

  • Most systems: ❌ The result sits in a queue until a clinician reviews it manually — hours or days later.
  • This system: 👍 An AI agent evaluates the trend, consults clinical guidelines, and generates evidence-based recommendations — in seconds, automatically.

No chatbot. No manual prompts. No black-box reasoning.

This is event-driven clinical decision support with full explainability:

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Triggered automatically by FHIR events
Multi-agent reasoning (context, guidelines, recommendations)
Complete audit trail in SQL (every decision, every evidence source)
FHIR-native outputs (DiagnosticReport published to server)

Built with:
- InterSystems IRIS for Health — Orchestration, FHIR, persistence, vector search
- CrewAI — Multi-agent framework for structured reasoning

You'll learn: 🖋️ How to orchestrate agentic AI workflows within production-grade interoperability systems — and why explainability matters more than accuracy alone.

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Hey Community,

Enjoy the new video on InterSystems Developers YouTube:

Advancing Healthcare Interoperability - Strategy and Vision @ Ready 2025

https://www.youtube.com/embed/_1mBIv-lGco
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