Some points: 

1. First ESB that allows you develop integrations using python, not java

2. Easy to create interoperability microservices, with support for kubernetes

3. you can create procedures and functions using python

4. you can create predictions and classifications using automl with sql language, very easy

5. in a same license you have, api gateway, esb, bi, database, reports and ML.

6. It is more easy create generative ia, because iris supports vector and python

7. Intersystems has the best dev community in the market, with comtests, gamifications with prizes, many articles, sample free apps.