Thanks for your answer.

When I stop Caché, all Cache.lck files are automaticaly destroy.

After that, I start Caché, I go check if the database are mount and it's not the case.

So, I click on the "globals" link and it only mount databases that was running good before.

All other database are not mount and I got an error message : 

ERREUR #5002: Erreur Cache: <NOTOPEN>GetGlobalDirectoryInfoFromDBInf+53^%SYS.DATABASE

Thanks for your help!