Thank you! I will try this.

Hi Enrico,

Thanks for your response,

The inbound message doesn't have MSH:18 value. I tried using UTF-18 but didn't work. Is there any possibility to resolve the issue to decode the characters correctly?

This is TCP HL7 Service using class 'EnsLib.HL7.Service.TCPService' and adapter is EnsLib.HL7.Adapter.TCPInboundAdapter. while occuring the issue I set Default Char Encoding as "!iso-8859-1" but it is not working as expected. It is converting utf8 charctaer to '?'.