At Ionate, we run plenty of enterprise applications and device-mapper works better. Please keep in mind that docker storage default for device mapper is 10GB. 

You can easily change it:

Docker in devicemapper and 50GB dm.size
 /etc/docker/daemon.json

{
    "storage-driver": "devicemapper",
    "storage-opts": [
    "dm.basesize=50G"
    ]
}

@Dmitry - Do you know how licensing  and support from Intersystems works for Cache on Linux. Also, have you seen any performance issues?

Thanks,