SSL/TLS error return from SSL_read()

First time setting up a SSL/TLS connection, and I am running into issues when I call it from within a Business Operation. I used openssl to generate a RSA 4096  SHA512 key/csr request for our Active Directory Certificate Service to generate a Certificate Chain for me to use within RedHat. I was 
able to connect to our Web Service server using a generic request from terminal, however when I try it from our Business Operation I am running into issues.

I tested the SSL/TLS connection using the following commands from the terminal...

DEVCLIN>set request=##class(%Net.HttpRequest).%New()
DEVCLIN>set request.Server = "ihisicbgnp.osumc.edu"
DEVCLIN>set request.Port=443
DEVCLIN>set request.SSLConfiguration="OSUWMC"
DEVCLIN>set request.Https=1
DEVCLIN>set tSC=request.Get("/",2)

and received a HTTP/1.1 200 OK back.
HTTP/1.1 200 OK
ACCEPT-RANGES: bytes
CACHE-CONTROL: private
CONTENT-ENCODING: gzip
CONTENT-LENGTH: 467
CONTENT-TYPE: text/html
DATE: Thu, 20 Jul 2023 20:08:54 GMT
ETAG: "b072b0f23afdd01:0"
LAST-MODIFIED: Fri, 02 Oct 2015 17:51:21 GMT
NTCOENT-LENGTH: 701
SERVER: Microsoft-IIS/8.5
X-POWERED-BY: ASP.NET.....

However if I try specifying the direct Web Service call from the Business Operation using the SSL/TLS configuration with that same HTTP server, but with the URL to the direct web service I am getting …. ERROR #6097: Error '<READ>Read+28^%Net.HttpRequest.1' while using TCP/IP device 
'9999'

I enabled
%SYS>d ^REDEBUG
 with FFFFFFFF flags and I am seeing...
a connection was made but then a SSL/TLS error return from SSL_read()
TCP connected to site 10.81.7.238 port 443
07/21/23-09:33:39:851 (3109066) 0 [Generic.Event] StreamInit: SNDBUF sys size=87040, dev size=0
07/21/23-09:33:39:851 (3109066) 0 [Generic.Event] StreamInit: RCVBUF sys size=369280, dev size=0
07/21/23-09:33:39:851 (3109066) 0 [Generic.Event] SSLconfig called - SSL_init = 0
07/21/23-09:33:39:851 (3109066) 0 [Generic.Event]
SSL/TLS configuration: OSUWMC
07/21/23-09:33:39:853 (3109066) 0 [Generic.Event]
TLS enabled versions, minimum: 16, maximum: 32
07/21/23-09:33:39:853 (3109066) 0 [Generic.Event]
Cipher list for TLSv1.2 and below: ALL:!aNULL:!eNULL:!EXP:!SSLv2
07/21/23-09:33:39:853 (3109066) 0 [Generic.Event]
Ciphersuites for TLSv1.3: TLS_AES_256_GCM_SHA384:TLS_CHACHA20_POLY1305_SHA256:TLS_AES_128_GCM_SHA256
07/21/23-09:33:39:853 (3109066) 0 [Generic.Event]
Certificate file: /etc/pki/ca-trust/source/anchors/int-lxiris-vd01.pem
07/21/23-09:33:39:853 (3109066) 0 [Generic.Event]
Private key file: /etc/pki/ca-trust/source/anchors/int-lxiris-vd01.key
07/21/23-09:33:39:853 (3109066) 0 [Generic.Event]
^MPeer verification option = 0, certificate depth = 9
07/21/23-09:33:39:853 (3109066) 0 [Generic.Event] OCSP Disabled for this SSL profile
07/21/23-09:33:39:853 (3109066) 0 [Generic.Event]
SSL/TLS client SSL_connect request.
07/21/23-09:33:39:864 (3109066) 0 [Generic.Event]
SSL/TLS error return from SSL_read().
07/21/23-09:33:39:864 (3109066) 0 [Generic.Event]
SSL_ERROR_SYSCALL: I/O error
is the RSA 4096 SHA512 certificate causing an issues since the Cipher suites do not specify RSA 4096 SHA512? Why would it work sending a generic request from Terminal but not from the Business Operation?