You can manage globals from a remote Java application by using the InterSystems Native API for Java. This API allows Java applications to connect to a remote InterSystems Caché or IRIS instance and directly access globals without requiring the application and database to run on the same machine.

Instead of relying on cacheextreme.jar, you can configure the connection parameters (host, port, namespace, username, and password) and interact with globals using the native API methods. This approach works well for applications deployed in containers or separate servers, as long as the database port is accessible within the network or VPN.

It provides a more flexible architecture and allows your Java service to read and update global nodes efficiently from a remote environment.