Studio is a client application, built using Caché objects, that runs on Windows-based operating systems. It can connect to any Caché server (compatible with the current version of Studio) regardless of what platform and operating system that server is using.
In the next few weeks, my coworkers are planning to start using VSCode to code with InterSystems' products. Among the many advantages of that, I would emphasize being able to connect with other technologies, such as GitHub, with ease. Besides, VSCode also offers an extensive extensions store, where you can find many free add-ons that make coding faster and more efficient. Last but not least, to conquer the heart of every developer, it is open source.