#Python

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Python is an interpreted high-level programming language for general-purpose programming. Created by Guido van Rossum and first released in 1991, Python has a design philosophy that emphasizes code readability, notably using significant whitespace

Official site.

InterSystems Python Binding Documentation.

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Article Tomo Okuyama · Mar 1 6m read

Why This Integration Matters

InterSystems continues to push AI capabilities forward natively in IRIS — vector search, MCP support, and Agentic AI capabilities. That roadmap is important, and there is no intention of stepping back from it.

But the AI landscape is also evolving in a way that makes ecosystem integration increasingly essential. Tools like Dify — an open-source, production-grade LLM orchestration platform — have become a serious part of enterprise AI stacks.

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Article Davi Massaru Teixeira Muta · Feb 24 9m read

Global Guard AI

1 Introduction

In environments that use InterSystems IRIS, globals are the physical foundation of data storage. Although system queries and administrative tools exist for metric inspection, global growth analysis is usually reactive: the problem is generally only noticed when there is disk pressure or performance impact.

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Article Yuri Marx · Feb 22 4m read

The facial recognition has become the most popular method for validating people's identities, thus enabling access to systems, confirmation of personal and documentary data, and approval of actions and documents.
The challenges are related to performance when the database is very large, accuracy, and especially the privacy of biometric facial data. For these challenges, nothing is better than using InterSystems Vector Search, as it allows:

  1. Performing vector searches in millions of records with much faster responses than traditional methods.
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Article Oliver Wilms · Feb 25 2m read

iris-budget

I created iris-budget app for the InterSystems Full Stack Contest in 2026. By full stack, we mean a frontend web or mobile application that inserts, updates, or deletes data in InterSystems IRIS via REST API, Native API, ODBC/JDBC, or Embedded Python.

My app uses multiple REST APIs to add a new category or retrieve a list of categories of expenses and income.

First web application /csp/coffee

I inherited /csp/coffee from module.xml in iris-fullstack-template.

Second web application /csp/budget

For this project, I created a swagger file called "budget.json.

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Article Ashok Kumar T · Feb 24 2m read

In the modern healthcare landscape, finding clinically similar patients often feels like looking for a needle in a haystack. Traditional keyword searches often fail because medical language is highly nuanced; a search for "Heart Failure" might miss a record containing "Congestive Cardiac Failure."

I am excited to share iris-medmatch, an AI-powered patient matching engine built on InterSystems IRIS for Health. By leveraging Vector Search, this tool understands clinical intent rather than just matching literal strings.

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Article Geet Kalra · Feb 18 6m read

Intersystems IRIS Productions provide a powerful framework for connecting disparate systems across various protocols and message formats in a reliable, observable, and scalable manner. intersystems_pyprod, short for InterSystems Python Productions, is a Python library that enables developers to build these interoperability components entirely in Python. Designed for flexibility, it supports a hybrid approach: you can seamlessly mix new Python-based components with existing ObjectScript-based ones, leveraging your established IRIS infrastructure.

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Article Suprateem Banerjee · Jan 25 14m read

 

Ever since I started using IRIS, I have wondered if we could create agents on IRIS. It seemed obvious: we have an Interoperability GUI that can trace messages, we have an underlying object database that can store SQL, Vectors and even Base64 images. We currently have a Python SDK that allows us to interface with the platform using Python, but not particularly optimized for developing agentic workflows. This was my attempt to create a Python SDK that can leverage several parts of IRIS to support development of agentic systems.

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Article Jorge Jaramillo Herrera · Jan 9 9m read

1-command only required for an entire IRIS instance for Data Science projects, and leveraging this to compare query methods' speed (Dynamic SQL, Pandas Query, and Globals).

Before joining InterSystems, I worked in a team of web developers as a data scientist. Most of my day-to-day work involved training and embedding ML models in Python-based backend applications through microservices, mainly built with the Django framework and using Postgres SQL for sourcing the data.

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Article Mihoko Iijima · Jan 31 31m read

Vector search is a retrieval method that converts text, images, audio, and other data into numeric vectors using an AI model, and then searches for items that are semantically close. It enables “semantic similarity search” from free text, which is difficult with keyword search alone.

However, in real use, I encountered cases where results that are “close in meaning” but logically the opposite appeared near the top of the search results.

This is a serious issue in situations where affirmation vs. negation matters. If the system returns the wrong answer, the impact can be significant, so we cannot ignore this problem.

This article does not propose a new algorithm. I wrote it to share a practical way I found useful when semantic search fails due to negation.

 

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Article Thomas Dyar · Jan 25 14m read

TL;DR: This article demonstrates how to run GraphRAG-style hybrid retrieval—combining vector similarity, graph traversal, and full-text search—entirely within InterSystems IRIS using the iris-vector-graph package. We use a fraud detection scenario to show how graph patterns reveal what vector search alone would miss.


Why Fraud Detection Needs Graphs

Every year, businesses and consumers lose billions to fraud. In 2024 alone, consumers reported $12.5 billion lost—a 25% increase year over year. What makes modern fraud so difficult to detect is that fraudsters rarely work alone.

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Article Barry Meyer · Jan 23 3m read

Senior engineering is defined not by the volume of code produced, but by the strategic avoidance of it. In complex integration environments, the tendency to utilize general-purpose libraries for every niche requirement introduces unnecessary overhead. True architectural maturity requires a commitment to "minimalist tooling"—prioritizing resilient, battle-tested system utilities over custom logic. This assessment examines our PGP encryption/decryption pipeline to demonstrate how shifting from application-level libraries to OS-native delegation enhances system durability.

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Article Gabriel Ing · Jan 16 5m read

Introduction

Earlier this year, I set about creating kit to introduce young techy folk at a Health Tech hackathon to using InterSystems IRIS for health, particularly focusing on using FHIR and vector search.

I wanted to publish this to the developer community because the tutorials included in the kit make a great introduction to using FHIR and to building a basic RAG system in IRIS.

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Article Ashok Kumar T · Dec 28, 2025 3m read

Embeddedpy-bridge: A Toolkit for Embedded Python

Overview

Embedded Python is a game-changer for InterSystems IRIS, offering access to the vast Python ecosystem directly within the database. However, bridging the gap between ObjectScript and Python can sometimes feel like translating between two different worlds.

To make this transition seamless using embeddedpy-bridge.

This package is a developer-centric utility kit designed to provide high-level ObjectScript wrappers, familiar syntax, and robust error handling for Embedded Python.

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Article Thomas Dyar · Dec 27, 2025 10m read

The Rut

Up until early this year, I haven't been not doing much coding at all -- I had gotten sick of it.

After many years as a hands-on software engineer and data scientist, I got burned out around 2015. I switched to business development roles focused on "external innovation," then joined InterSystems in 2019 as a product manager. I missed the creative aspects of coding, but not the tedium. The endless cycle of boilerplate, debugging, and context-switching had left me creatively depleted.

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Article André Dienes Friedrich · Dec 26, 2025 5m read

How to Build Applications with LangGraph: A Step-by-Step Guide

Tags: #LangGraph #LangChain #AI #Agents #Python #LLM #StateManagement #Workflows


Hi everyone, I want to tell you a little about LangGraph, a tool that I'm studying and developing.

Basically traditional AI applications often face challenges when dealing with complex workflows and dynamic states. LangGraph offers a robust solution, enabling the creation of stateful agents that can manage complex conversations, make context-based decisions, and execute sophisticated workflows.

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Article Henry Pereira · Apr 2, 2025 17m read

Image generated by OpenAI DALL·E

I'm a huge sci-fi fan, but while I'm fully onboard the Star Wars train (apologies to my fellow Trekkies!), but I've always appreciated the classic episodes of Star Trek from my childhood. The diverse crew of the USS Enterprise, each masterminding their unique roles, is a perfect metaphor for understanding AI agents and their power in projects like Facilis. So, let's embark on an intergalactic mission, leveraging AI as our ship's crew and  boldly go where no man has gone before!

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Article Muhammad Waseem · Dec 8, 2025 4m read


Apache Airflow is the leading open-source platform to programmatically author, schedule, and monitor data pipelines and workflows using Python. Workflows are defined as code (DAGs), making them version-controlled, testable, and reusable. With a rich UI, 100+ built-in operators, dynamic task generation, and native support for cloud providers, Airflow powers ETL/ELT, ML pipelines, and batch jobs at companies like Airbnb, Netflix, and Spotify.

Airflow Application Layout
Dag Details Page in light mode showing overview dashboard and failure diagnostics

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Article Emil Polakiewicz · Dec 8, 2025 19m read

How to set up RAG for OpenAI agents using IRIS Vector DB in Python

In this article, I’ll walk you through an example of using InterSystems IRIS Vector DB to store embeddings and integrate them with an OpenAI agent.

To demonstrate this, we’ll create an OpenAI agent with knowledge of InterSystems technology. We’ll achieve this by storing embeddings of some InterSystems documentation in IRIS and then using IRIS vector search to retrieve relevant content—enabling a Retrieval-Augmented Generation (RAG) workflow.

Note: Section 1 details how process text into embeddings.

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Article Rodolfo Pscheidt Jr · Mar 17, 2025 2m read

 

In this article I will be discussing the use of an alternative LLM for generative IA. OpenIA is commonly used, in this article I will show you how to use it and the advantages of using Ollama

In the generative AI usage model that we are used to, we have the following flow:

  • we take texts from a data source (a file, for example) and embedding that text into vectors
  • we store the vectors in an IRIS database.
  • we call an LLM (Large Language Model) that accesses these vectors as context to generate responses in human language.
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Article Julio Esquerdo · Nov 21, 2025 1m read

Hi,

When we open a terminal in IRIS, we are entering the ObjectScript shell. Within this shell, we can execute IRIS commands, such as:

In other words, the ObjectScript command is executed in the current shell. But it's always good to remember that IRIS has other shells

  • SQL
  • Python
  • TSQL
  • MDX

One very interesting aspect is shortcuts. We can access these shells through their calls or via shortcuts, as shown in the table below:

 




Shell

Call

Shortcut

SQL

Do $SYSTEM.SQL.Shell()

:sql

Python

Do $SYSTEM.Python.Shell

:py

TSQL

Do $SYSTEM.SQL.

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Article Muhammad Waseem · Nov 20, 2025 13m read

Hi Community,

In the first part of this series, we examined the fundamentals of Interoperability on Python (IoP), specifically how it enables us to construct such interoperability elements as business services, processes, and operations using pure Python.

Now, we are ready to take things a step further. Real-world integration scenarios extend beyond simple message handoffs.They involve scheduled polling, custom message structures, decision logic, filtering, and configuration handling.In this article, we will delve into these more advanced IoP capabilities and demonstrate how to create and run a more complex interoperability flow using only Python.

To make it practical, we will build a comprehensive example: The Reddit Post Analyzer Production. The concept is straightforward: continuously retrieving the latest submissions from a chosen subreddit, filtering them based on popularity, adding extra tags to them, and sending them off for storage or further analysis.

The ultimate goal here is a reliable, self-running data ingestion pipeline. All major parts (the Business Service, Business Process, and Business Operation) are implemented in Python, showcasing how to use IoP as a Python-first integration methodology.

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Article Thomas Dyar · Mar 25, 2025 2m read

Introduction

In InterSystems IRIS 2024.3 and subsequent IRIS versions, the AutoML component is now delivered as a separate Python package that is installed after installation. Unfortunately, some recent versions of Python packages that AutoML relies on have introduced incompatibilities, and can cause failures when training models (TRAIN MODEL statement). If you see an error mentioning "TypeError" and the keyword argument "fit_params" or "sklearn_tags", read on for a quick fix.

Root Cause

  • scikit-learn updated to version 1.6.0, deprecating fit_params.
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Article Kate Lau · Oct 13, 2025 13m read

 

Hi all,

 

Let's do some more work about the testing data generation and export the result by REST API.😁

Here, I would like to reuse the datagen.restservice class which built in the pervious article Writing a REST api service for exporting the generated patient data in .csv

This time, we are planning to generate a FHIR bundle include multiple resources for testing the FHIR repository.

Here is some reference for you, if you want to know mare about FHIR The Concept of FHIR: A Healthcare Data Standard Designed for the Future

 

OK... Let's start😆

1. Create a new utility class datagen.utli.

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Article Kate Lau · Oct 13, 2025 5m read

Hi all,

 

It's me again 😁. In the pervious article Writing a REST api service for exporting the generated FHIR bundle in JSON, we actually generated a resource DocumentReference, with the content data encoded in Base64

 

Question!! Is it possible to write a REST service for decoding it? Because I am very curious what is the message data talking about🤔🤔🤔

OK, Let's start!

1. Create a new utility class datagen.utli.decodefhirjson.cls for decoding the data inside the DocumentReference
 

Class datagen.utli.decodefhirjson Extends %RegisteredObject
{
}

2. Write a Python function decodebase64docref to 
a

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Article Kate Lau · Oct 9, 2025 6m read

Hi,

 

It's me again😁, recently I am working on generating some fake patient data for testing purpose with the help of Chat-GPT by using Python. And, at the same time I would like to share my learning curve.😑

1st of all for building a custom REST api service is easy by extending the %CSP.REST

Creating a REST Service Manually

Let's Start !😂

1. Create a class datagen.restservice which extends  %CSP.REST 

Class datagen.restservice Extends %CSP.REST
{
Parameter CONTENTTYPE = "application/json";
}

 

2.

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Article Pietro Di Leo · Oct 9, 2025 6m read

Introduction

In my previous article, I introduced the FHIR Data Explorer, a proof-of-concept application that connects InterSystems IRIS, Python, and Ollama to enable semantic search and visualization over healthcare data in FHIR format, a project currently participating in the InterSystems External Language Contest.

In this follow-up, we’ll see how I integrated Ollama for generating patient history summaries directly from structured FHIR data stored in IRIS, using lightweight local language models (LLMs) such as Llama 3.2:1B or Gemma 2:2B.

The goal was to build a completely local AI pipeline that can extract, format, and narrate patient histories while keeping data private and under full control.

All patient data used in this demo comes from FHIR bundles, which were parsed and loaded into IRIS via the IRIStool module. This approach makes it straightforward to query, transform, and vectorize healthcare data using familiar pandas operations in Python. If you’re curious about how I built this integration, check out my previous article Building a FHIR Vector Repository with InterSystems IRIS and Python through the IRIStool module.

Both IRIStool and FHIR Data Explorer are available on the InterSystems Open Exchange — and part of my contest submissions. If you find them useful, please consider voting for them!

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Article Pietro Di Leo · Oct 9, 2025 4m read

Introduction

In a previous article, I presented the IRIStool module, which seamlessly integrates the pandas Python library with the IRIS database. Now, I'm explaining how we can use IRIStool to leverage InterSystems IRIS as a foundation for intelligent, semantic search over healthcare data in FHIR format.

This article covers what I did to create the database for another of my projects, the FHIR Data Explorer. Both projects are candidates in the current InterSystems contest, so please vote for them if you find them useful.

You can find them at the Open Exchange:

In this article we'll cover:

  • Connecting to InterSystems IRIS database through Python
  • Creating a FHIR-ready database schema
  • Importing FHIR data with vector embeddings for semantic search
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Article Pietro Di Leo · Oct 6, 2025 4m read
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Article Pietro Di Leo · Oct 6, 2025 5m read

Hi everyone! 👋
I’m excited to share the project I’ve submitted to the current InterSystems .Net, Java, Python, and JavaScript Contest — it’s called IRIStool and Data Manager, and you can find it on the InterSystems Open Exchange and on my GitHub page.

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